KipR

• Description: transcriptional repressor of the kip operon
  
  

Gene name	kipR
Synonyms	ycsO
Essential	no
Product	transcriptional regulator
Function	regulation of sporulation initiation
Function and regulation of this protein in SubtiPathways: Phosphorelay
MW, pI	27 kDa, 5.435
Gene length, protein length	738 bp, 246 aa
Immediate neighbours	kipA, lipC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control, phosphorelay

This gene is a member of the following regulons

KipR regulon, TnrA regulon

The KipR regulon:

• ycsF-ycsG-ycsI-kipI-kipA-kipR-lipC

The gene

Basic information

• Locus tag: BSU04100

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P42968

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ycsF-ycsG-ycsI-kipI-kipA-kipR-lipC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • KipR: transcription repression PubMed
  • TnrA: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

L Wang, R Grau, M Perego, J A Hoch
A novel histidine kinase inhibitor regulating development in Bacillus subtilis.
Genes Dev: 1997, 11(19);2569-79
[PubMed:9334321] [WorldCat.org] [DOI] (P p)