Difference between revisions of "YodB"
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| − | * '''Description:''' MarR/DUF24 | + | * '''Description:''' [[MarR/DUF24 family]] transcription repressor of ''[[azoR1]]'', ''[[catD]]-[[catE]]'' and ''[[yodC]]'' expression <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || MarR/DUF24 | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[MarR/DUF24 family]] transcription repressor |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of quinone and diamide detoxification | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of quinone and diamide detoxification | ||
| Line 47: | Line 47: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | increased resistance to catechol, quinones and diamide {{PubMed|20639328}} | + | * increased resistance to catechol, quinones and diamide {{PubMed|20639328}} |
=== Database entries === | === Database entries === | ||
| Line 65: | Line 65: | ||
* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| − | * '''Protein family:''' MarR/DUF24 | + | * '''Protein family:''' [[MarR/DUF24 family]] |
* '''Paralogous protein(s):''' [[CatR]] | * '''Paralogous protein(s):''' [[CatR]] | ||
Revision as of 09:06, 17 January 2012
- Description: MarR/DUF24 family transcription repressor of azoR1, catD-catE and yodC expression
| Gene name | yodB |
| Synonyms | |
| Essential | no |
| Product | MarR/DUF24 family transcription repressor |
| Function | regulation of quinone and diamide detoxification |
| MW, pI | 12 kDa, 4.737 |
| Gene length, protein length | 336 bp, 112 aa |
| Immediate neighbours | yodA, yodC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transcription factors and their control, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The YodB regulon:
The gene
Basic information
- Locus tag: BSU19540
Phenotypes of a mutant
- increased resistance to catechol, quinones and diamide PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: MarR/DUF24 family
- Paralogous protein(s): CatR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: redox-controlled by intersubunit disulfide formation of Cys6 and Cys101' in response to quinones and diamide
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34844
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- subject to autorepression PubMed
- Regulatory mechanism:
- YodB: transcription repression PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Haike Antelmann,University of Greifswald, Germany
Your additional remarks
References
Reviews
Antelmann H, Helmann JD. Thiol-based redox switches and gene regulation. Antioxid Redox Signal. 2011,14:1049-63. PubMed
Haike Antelmann, Michael Hecker, Peter Zuber
Proteomic signatures uncover thiol-specific electrophile resistance mechanisms in Bacillus subtilis.
Expert Rev Proteomics: 2008, 5(1);77-90
[PubMed:18282125]
[WorldCat.org]
[DOI]
(I p)
Original Publications
