Difference between revisions of "SppA"
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=== Additional information=== | === Additional information=== | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** serine protease that functions to cleave the remnant signal peptides left behind after [[protein secretion]] and cleavage by signal peptidases | ||
* '''Protein family:''' peptidase S49 family (according to Swiss-Prot) | * '''Protein family:''' peptidase S49 family (according to Swiss-Prot) | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** the protein forms a dome shaped octameric complex {{PubMed|22472423}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| − | ** cell membrane | + | ** cell membrane {{PubMed|22472423}} |
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=3RST 3RST] {{PubMed|22472423}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34525 O34525] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34525 O34525] | ||
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=References= | =References= | ||
| − | <pubmed>9987136,12207695 </pubmed> | + | <pubmed>9987136,12207695 22472423 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:26, 5 April 2012
- Description: signal peptide peptidase required for efficient processing of pre-proteins
| Gene name | sppA |
| Synonyms | yteI |
| Essential | no |
| Product | signal peptide peptidase |
| Function | protein secretion |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 36 kDa, 7.314 |
| Gene length, protein length | 1005 bp, 335 aa |
| Immediate neighbours | yteJ, ytdI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
protein secretion, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29530
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- serine protease that functions to cleave the remnant signal peptides left behind after protein secretion and cleavage by signal peptidases
- Protein family: peptidase S49 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- the protein forms a dome shaped octameric complex PubMed
- Localization:
- cell membrane PubMed
Database entries
- UniProt: O34525
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
