Difference between revisions of "MscL"
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* '''Operon:''' ''mscL'' {{PubMed|9353933}} | * '''Operon:''' ''mscL'' {{PubMed|9353933}} | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mscL_3743267_3743659_-1 mscL] {{PubMed|22383849}} |
+ | |||
+ | * '''Sigma factor:''' | ||
* '''Regulation:''' expressed in logarithmic phase [http://www.ncbi.nlm.nih.gov/sites/entrez/19252899 PubMed] | * '''Regulation:''' expressed in logarithmic phase [http://www.ncbi.nlm.nih.gov/sites/entrez/19252899 PubMed] |
Revision as of 08:04, 17 April 2012
- Description: large conductance mechanosensitive channel protein, prevents selective release of cytoplasmic proteins in a hypotonic environment
Gene name | mscL |
Synonyms | ywpC |
Essential | no |
Product | large conductance mechanosensitive channel protein |
Function | resistance to osmotic downshockglycine betaine export |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 14 kDa, 4.649 |
Gene length, protein length | 390 bp, 130 aa |
Immediate neighbours | ywpD, ywpB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
coping with hypo-osmotic stress, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU36360
Phenotypes of a mutant
sensitive to osmotic downshock (> 0.5 M) during logarithmic growth PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: mscL family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- UniProt: P94585
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: mscL PubMed
- Sigma factor:
- Regulation: expressed in logarithmic phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Jan Maarten van Dijl, Groningen, Netherlands
Erhard Bremer, University of Marburg, Germany homepage
Your additional remarks
References
Reviews
Original Publications