BsrA

• Description: 6S RNA
  
  

Gene name	bsrA
Synonyms
Essential	no
Product	6S RNA
Function	antagonist of SigA
Gene length	190 bp
Immediate neighbours	yrvM, aspS
Gene sequence (+200bp)
Genetic context

Categories containing this gene/protein

sigma factors and their control, ncRNA

The gene

Basic information

• Locus tag:

Phenotypes of a mutant

• reduced growth rate PubMed
• delayed outgrowth from stationary phase PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: no entry

• Structure:

Additional information

• Similar RNA: bsrB

• Interactions: BsrA-SigA-RNA polymerase

Expression and regulation

• Operon: bsrA PubMed

• Sigma factor: SigA PubMed

• Regulation: expressed in vegetative cells PubMed

• Regulatory mechanism:

• Additional information: transcribed as 201 nt RNA, processed to mature 190 bp 6S RNA PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

Labs working on this gene/RNA

Kouji Nakamura, Tsukuba, University, Japan

Roland Hartmann, Philipps-Universität Marburg, Marburg, Germany, Homepage

References

Additional publications: PubMed

Jeffrey E Barrick, Narasimhan Sudarsan, Zasha Weinberg, Walter L Ruzzo, Ronald R Breaker
6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter.
RNA: 2005, 11(5);774-84
[PubMed:15811922] [WorldCat.org] [DOI] (P p)

Satoru Suzuma, Sayaka Asari, Keigo Bunai, Keiko Yoshino, Yoshinari Ando, Hiroshi Kakeshita, Masaya Fujita, Kouji Nakamura, Kunio Yamane
Identification and characterization of novel small RNAs in the aspS-yrvM intergenic region of the Bacillus subtilis genome.
Microbiology (Reading): 2002, 148(Pt 8);2591-2598
[PubMed:12177353] [WorldCat.org] [DOI] (P p)