Difference between revisions of "YfiT"
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| − | * '''Description:''' | + | * '''Description:''' bacillithiol S-transferase <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || bacillithiol S-transferase |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || detoxification |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 20 kDa, 6.612 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 20 kDa, 6.612 | ||
Revision as of 10:01, 9 November 2011
- Description: bacillithiol S-transferase
| Gene name | yfiT |
| Synonyms | |
| Essential | no |
| Product | bacillithiol S-transferase |
| Function | detoxification |
| MW, pI | 20 kDa, 6.612 |
| Gene length, protein length | 534 bp, 178 aa |
| Immediate neighbours | yfiS, yfiU |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
poorly characterized/ putative enzymes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU08390
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: metal hydrolase yfiT family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): Ni(2+) PubMed
- Effectors of protein activity:
- Interactions: homodimer PubMed
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1RXQ
- UniProt: O31562
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: yfiT (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Gerald L Newton, Stephan S Leung, Judy I Wakabayashi, Mamta Rawat, Robert C Fahey
The DinB superfamily includes novel mycothiol, bacillithiol, and glutathione S-transferases.
Biochemistry: 2011, 50(49);10751-60
[PubMed:22059487]
[WorldCat.org]
[DOI]
(I p)
Shyamala S Rajan, Xiaojing Yang, Ludmilla Shuvalova, Frank Collart, Wayne F Anderson
YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology.
Biochemistry: 2004, 43(49);15472-9
[PubMed:15581359]
[WorldCat.org]
[DOI]
(P p)
