GerPA

• Description: spore germination protein
  
  

Gene name	gerPA
Synonyms	yisH
Essential	no
Product	unknown
Function	germination
MW, pI	7 kDa, 4.464
Gene length, protein length	219 bp, 73 aa
Immediate neighbours	gerPB, yisI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

germination

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU10720

Expression

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerPA/gerPF family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O06721

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerPA-gerPB-gerPC-gerPD-gerPE-gerPF (according to DBTBS)

• Sigma factor: SigK PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigK) PubMed
  • subject to negative regulation by GerE PubMed

• Regulatory mechanism:

• Additional information:
  • A ncRNA is predicted between gerPA and yisI PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

J Behravan, H Chirakkal, A Masson, A Moir
Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus affect access of germinants to their targets in spores.
J Bacteriol: 2000, 182(7);1987-94
[PubMed:10715007] [WorldCat.org] [DOI] (P p)