Difference between revisions of "FtsZ"
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** bundling of FtsZ protofilaments into strikingly long and regular tubular structures reminiscent of eukaryotic microtubules requires the prior formation of large ring polymers of [[SepF]] {{PubMed|21224850}} | ** bundling of FtsZ protofilaments into strikingly long and regular tubular structures reminiscent of eukaryotic microtubules requires the prior formation of large ring polymers of [[SepF]] {{PubMed|21224850}} | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
** [[FtsZ]]-[[ZapA]] {{PubMed|19843223}} | ** [[FtsZ]]-[[ZapA]] {{PubMed|19843223}} | ||
** [[FtsZ]]-[[EzrA]] {{PubMed|10449747}} | ** [[FtsZ]]-[[EzrA]] {{PubMed|10449747}} | ||
| Line 95: | Line 95: | ||
** [[FtsZ]]-[[SepF]] {{PubMed|16420366}} | ** [[FtsZ]]-[[SepF]] {{PubMed|16420366}} | ||
| − | * '''Localization:''' | + | * '''[[Localization]]:''' |
** septal at the cell membrane {{PubMed|20566861}} | ** septal at the cell membrane {{PubMed|20566861}} | ||
** septal localization partially depends on the proton motive force {{PubMed|20566861}} | ** septal localization partially depends on the proton motive force {{PubMed|20566861}} | ||
Revision as of 16:48, 10 August 2011
- Description: cell-division initiation protein (septum formation)
| Gene name | ftsZ |
| Synonyms | ts-1 |
| Essential | yes PubMed |
| Product | cell-division initiation protein (septum formation) |
| Function | formation of Z-ring |
| Interactions involving this protein in SubtInteract: FtsZ | |
| MW, pI | 40 kDa, 4.814 |
| Gene length, protein length | 1146 bp, 382 aa |
| Immediate neighbours | ftsA, bpr |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
cell division, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15290
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ftsZ family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P17865
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody: available in the Jeff Errington lab
Labs working on this gene/protein
- Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage
- Leendert Hamoen, CBCB, Newcastle University, UK
Your additional remarks
References
Reviews
Additional reviews: PubMed
FtsZ as antibacterial drug target
Other original Publications
Additional publications: PubMed
