QdoR

• Description: transcriptional regulator, control of qdoI-yxaH and lmrA-lmrB
  
  

Gene name	qdoR
Synonyms	yxaF
Essential	no
Product	transcriptional regulator
Function	control of quercetin utilization
MW, pI	20 kDa, 6.111
Gene length, protein length	573 bp, 191 aa
Immediate neighbours	qdoI, yxnA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

LmrA regulon, QdoR regulon

The QdoR regulon:

• qdoI-yxaH, qdoR

The gene

Basic information

• Locus tag: BSU39990

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): LmrA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: flavonoids such as quercetin act as molecular inducers and result in release from DNA targets PubMed

• Interactions:

• Localization:

Database entries

• Structure: 1SGM

• UniProt: P42105

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: qdoR PubMed

• Sigma factor:

• Regulation:
  • induced by flavonoids such as quercetin (QdoR, LmrA) PubMed

• Regulatory mechanism:
  • LmrA: transcription repression PubMed
  • QdoR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Yasutaro Fujita, University of Fukuyama, Japan