BpsB

• Description: methyltransferase, involved in polyketide synthesis
  
  

Gene name	bpsB
Synonyms	ypbQ
Essential	no
Product	methyltransferase
Function	polyketide synthesis
MW, pI	19 kDa, 9.551
Gene length, protein length	504 bp, 168 aa
Immediate neighbours	fbpC, bpsA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

The gene

Basic information

• Locus tag: BSU22040

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: conversion of triketide pyrones to alkylpyrone methyl ethers PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P54158

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: bpsA-bpsB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • A ncRNA is predicted between dynA and bpsB PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Chiaki Nakano, Hiroki Ozawa, Genki Akanuma, Nobutaka Funa, Sueharu Horinouchi
Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.
J Bacteriol: 2009, 191(15);4916-23
[PubMed:19465653] [WorldCat.org] [DOI] (I p)