Difference between revisions of "FeuB"

From SubtiWiki
Jump to: navigation, search
Line 12: Line 12:
 
|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] for the siderophores Fe-enterobactin <br/>and Fe-bacillibactin (integral membrane protein)
 
|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] for the siderophores Fe-enterobactin <br/>and Fe-bacillibactin (integral membrane protein)
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || iron acquisition
+
|style="background:#ABCDEF;" align="center"|'''Function''' || [[acquisition of iron]]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/FeuB FeuB]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://cellpublisher.gobics.de/view/GqbblRJkBH Metal ion homeostasis]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://cellpublisher.gobics.de/view/GqbblRJkBH Metal ion homeostasis]'''

Revision as of 15:34, 29 July 2011

  • Description: ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)

Gene name feuB
Synonyms
Essential no
Product ABC transporter for the siderophores Fe-enterobactin
and Fe-bacillibactin (integral membrane protein)
Function acquisition of iron
Interactions involving this protein in SubtInteract: FeuB
Metabolic function and regulation of this protein in SubtiPathways:
Stress, Metal ion homeostasis
MW, pI 35 kDa, 9.539
Gene length, protein length 1002 bp, 334 aa
Immediate neighbours feuC, feuA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FeuB context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Btr regulon, CitB regulon, Fur regulon

The gene

Basic information

  • Locus tag: BSU01620

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: FecCD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of iron (Fur, CitB) PubMed
    • induced in the presence of iron chelators bacillibactin or enterobactin (Btr) PubMed
  • Regulatory mechanism:
    • Fur: transcription repression PubMed
    • CitB: binding to the iron responsive element in the absence of iron
    • Btr: transcription activation in the presence of the co-activators bacillibactin or enterobactin PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References