NadR

• Description: transcriptional repressor of genes involved in NAD biosynthesis
  
  

Gene name	nadR
Synonyms	yrxA
Essential	no
Product	transcriptional repressor
Function	regulation of NAD biosynthesis
MW, pI	19 kDa, 5.759
Gene length, protein length	534 bp, 178 aa
Immediate neighbours	nifS, pheA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis of cofactors, transcription factors and their control

This gene is a member of the following regulons

NadR regulon

The NadR regulon:

• nadB-nadC-nadA, nadR-nifS

The gene

Basic information

• Locus tag: BSU27890

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39667

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: nifS-nadR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of nicotinic acid (NadR) PubMed

• Regulatory mechanism:
  • NadR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage