Difference between revisions of "SufS"
| Line 63: | Line 63: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' transfer of iron to [[SufU]] {{PubMed|21236255}} |
* '''Protein family:''' Csd subfamily (according to Swiss-Prot) | * '''Protein family:''' Csd subfamily (according to Swiss-Prot) | ||
| Line 81: | Line 81: | ||
* '''Effectors of protein activity:''' interaction with [[SufU]] enhances the activity of [[SufS]] 40-fold {{PubMed|20097860}} | * '''Effectors of protein activity:''' interaction with [[SufU]] enhances the activity of [[SufS]] 40-fold {{PubMed|20097860}} | ||
| − | * '''Interactions:''' [[SufS]]-[[SufU]] {{PubMed|20097860}} | + | * '''Interactions:''' [[SufS]]-[[SufU]] {{PubMed|20097860,21236255}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 129: | Line 129: | ||
=References= | =References= | ||
<pubmed> 20097860 20822158 </pubmed> | <pubmed> 20097860 20822158 </pubmed> | ||
| + | '''Additional publications:''' {{PubMed|21236255}} | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:22, 19 January 2011
- Description: cysteine desulfurase
| Gene name | sufS |
| Synonyms | yurW, csd |
| Essential | yes PubMed |
| Product | cysteine desulfurase |
| Function | formation of iron-sulfur clusters in proteins |
| MW, pI | 44 kDa, 5.199 |
| Gene length, protein length | 1218 bp, 406 aa |
| Immediate neighbours | sufU, sufD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
iron metabolism, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU32690
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Protein family: Csd subfamily (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Localization:
Database entries
- Structure:
- UniProt: O32164
- KEGG entry: [2]
- E.C. number: 2.8.1.7
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Bruna Selbach, Emily Earles, Patricia C Dos Santos
Kinetic analysis of the bisubstrate cysteine desulfurase SufS from Bacillus subtilis.
Biochemistry: 2010, 49(40);8794-802
[PubMed:20822158]
[WorldCat.org]
[DOI]
(I p)
Alexander G Albrecht, Daili J A Netz, Marcus Miethke, Antonio J Pierik, Olaf Burghaus, Florian Peuckert, Roland Lill, Mohamed A Marahiel
SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis.
J Bacteriol: 2010, 192(6);1643-51
[PubMed:20097860]
[WorldCat.org]
[DOI]
(I p)
Additional publications: PubMed
