Difference between revisions of "PurN"
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=== Database entries === | === Database entries === | ||
− | * '''Structure:''' [http://www.rcsb.org/pdb/ | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=3P9X 3P9X] (from ''B. halodurans'', 51% identity, 70% similarity) |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P12040 P12040] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P12040 P12040] |
Revision as of 12:18, 19 February 2011
- Description: phosphoribosylglycinamide formyltransferase, irreversible
Gene name | purN |
Synonyms | |
Essential | no |
Product | phosphoribosylglycinamide formyltransferase |
Function | purine biosynthesis |
Metabolic function and regulation of this protein in SubtiPathways: Purine synthesis, Nucleotides (regulation) | |
MW, pI | 21 kDa, 6.182 |
Gene length, protein length | 585 bp, 195 aa |
Immediate neighbours | purM, purH |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06510
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide (according to Swiss-Prot)
- Protein family: GART family (according to Swiss-Prot)
- Paralogous protein(s): YkkE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 3P9X (from B. halodurans, 51% identity, 70% similarity)
- UniProt: P12040
- KEGG entry: [3]
- E.C. number: 2.1.2.2
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References