Difference between revisions of "YqeH"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[translation]]}}, | ||
| + | {{SubtiWiki category|[[essential genes]]}}, | ||
| + | {{SubtiWiki category|[[GTP-binding proteins]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
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=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 21:35, 8 December 2010
- Description: assembly/ stability of the 30S subunit of the ribosome, assembly of the 70S ribosome
| Gene name | yqeH |
| Synonyms | |
| Essential | yes PubMed |
| Product | GTPase |
| Function | ribosome assembly |
| MW, pI | 40 kDa, 6.009 |
| Gene length, protein length | 1098 bp, 366 aa |
| Immediate neighbours | aroD, yqeG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
translation, essential genes, GTP-binding proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25670
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Binds and hydrolyzes GTP and readily exchanges GDP for GTP
- Protein family: Era/Obg family
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 3EC1 (Geobacillus stearothermophilus)
- UniProt: P54453
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Naotake Ogasawara, Nara, Japan
Your additional remarks
References
Reviews
Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570]
[WorldCat.org]
[DOI]
(I p)
Original publications
Baskaran Anand, Parag Surana, Balaji Prakash
Deciphering the catalytic machinery in 30S ribosome assembly GTPase YqeH.
PLoS One: 2010, 5(4);e9944
[PubMed:20376346]
[WorldCat.org]
[DOI]
(I e)
Baskaran Anand, Parag Surana, Sagar Bhogaraju, Sushmita Pahari, Balaji Prakash
Circularly permuted GTPase YqeH binds 30S ribosomal subunit: Implications for its role in ribosome assembly.
Biochem Biophys Res Commun: 2009, 386(4);602-6
[PubMed:19540197]
[WorldCat.org]
[DOI]
(I p)
Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, Taku Oshima, Naotake Ogasawara
The GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis.
Genes Genet Syst: 2007, 82(4);281-9
[PubMed:17895579]
[WorldCat.org]
[DOI]
(P p)
William C Uicker, Laura Schaefer, Mark Koenigsknecht, Robert A Britton
The essential GTPase YqeH is required for proper ribosome assembly in Bacillus subtilis.
J Bacteriol: 2007, 189(7);2926-9
[PubMed:17237168]
[WorldCat.org]
[DOI]
(P p)
Takuya Morimoto, Pek Chin Loh, Tomohiro Hirai, Kei Asai, Kazuo Kobayashi, Shigeki Moriya, Naotake Ogasawara
Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis.
Microbiology (Reading): 2002, 148(Pt 11);3539-3552
[PubMed:12427945]
[WorldCat.org]
[DOI]
(P p)
