Difference between revisions of "PdxK"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[biosynthesis of cofactors]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
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=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 00:36, 9 December 2010
- Description: pyridoxine, pyridoxal, and pyridoxamine kinase
| Gene name | pdxK |
| Synonyms | ywdB, ipa-52r, thiD |
| Essential | no |
| Product | pyridoxine, pyridoxal, and pyridoxamine kinase |
| Function | biosynthesis of pyridoxal phosphate |
| MW, pI | 28 kDa, 4.922 |
| Gene length, protein length | 813 bp, 271 aa |
| Immediate neighbours | ywdC, ywdA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38020
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine (according to Swiss-Prot)
- Protein family: thiD family (according to Swiss-Prot)
- Paralogous protein(s): ThiD
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 2IB5
- UniProt: P39610
- KEGG entry: [3]
- E.C. number: 2.7.4.7
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Operon: pdxK PubMed
- Regulation:
- Regulatory mechanism:
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
