Difference between revisions of "PaiA"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[miscellaneous metabolic pathways]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
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=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 23:03, 8 December 2010
- Description: spermine/spermidine-N-acetyltransferase
| Gene name | paiA |
| Synonyms | |
| Essential | no |
| Product | spermine/spermidine-N-acetyltransferase |
| Function | control of intracellular polyamine concentrations |
| MW, pI | 19 kDa, 5.018 |
| Gene length, protein length | 516 bp, 172 aa |
| Immediate neighbours | paiB, sufA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU32150
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 1TIQ
- UniProt: P21340
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Farhad Forouhar, Alexandre Kuzin, Jayaraman Seetharaman, Insun Lee, Weihong Zhou, Mariam Abashidze, Yang Chen, Wei Yong, Haleema Janjua, Yingyi Fang, Dongyan Wang, Kellie Cunningham, Rong Xiao, Thomas B Acton, Eran Pichersky, Daniel F Klessig, Carl W Porter, Gaetano T Montelione, Liang Tong
Functional insights from structural genomics.
J Struct Funct Genomics: 2007, 8(2-3);37-44
[PubMed:17588214]
[WorldCat.org]
[DOI]
(P p)
Farhad Forouhar, In-Sun Lee, Jelena Vujcic, Slavoljub Vujcic, Jianwei Shen, Sergey M Vorobiev, Rong Xiao, Thomas B Acton, Gaetano T Montelione, Carl W Porter, Liang Tong
Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase.
J Biol Chem: 2005, 280(48);40328-36
[PubMed:16210326]
[WorldCat.org]
[DOI]
(P p)
T Urano, H Ihara, K Umemura, Y Suzuki, M Oike, S Akita, Y Tsukamoto, I Suzuki, A Takada
The profibrinolytic enzyme subtilisin NAT purified from Bacillus subtilis Cleaves and inactivates plasminogen activator inhibitor type 1.
J Biol Chem: 2001, 276(27);24690-6
[PubMed:11325965]
[WorldCat.org]
[DOI]
(P p)
