Difference between revisions of "YabA"
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| − | + | * '''Description:''' tethers [[DnaA]] to the polymerase-clamp protein [[DnaN]] <br/><br/> | |
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| − | * '''Description:''' tethers [[DnaA]] to the polymerase-clamp protein [[DnaN]] | ||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yaaT]]'', ''[[yabB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yaaT]]'', ''[[yabB]]'' | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+& | + | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB11809]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
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| − | |colspan="2" | '''Genetic context''' | + | |colspan="2" | '''Genetic context''' <br/> [[Image:yabA_context.gif]] |
| − | + | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | |
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__TOC__ | __TOC__ | ||
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=The gene= | =The gene= | ||
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=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| − | [[Philippe Noirot]], Jouy-en-Josas, France [http://locus.jouy.inra.fr/cms/index.php?id=18 Homepage] | + | [[Philippe Noirot]], Jouy-en-Josas, France [http://locus.jouy.inra.fr/cms/index.php?id=18 Homepage]<br> |
[[Alan Grossman]], Cambridge, MA, USA [http://web.mit.edu/biology/www/facultyareas/facresearch/grossman.html Homepage] | [[Alan Grossman]], Cambridge, MA, USA [http://web.mit.edu/biology/www/facultyareas/facresearch/grossman.html Homepage] | ||
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=References= | =References= | ||
==Reviews== | ==Reviews== | ||
| − | + | <pubmed> 20157337 </pubmed> | |
==Original publications== | ==Original publications== | ||
| − | + | <pubmed> 19578359,,12060778 16461910, 19737352 19081080 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 04:58, 24 November 2010
| Gene name | yabA |
| Synonyms | |
| Essential | no |
| Product | negative regulator of replication initiation |
| Function | positioning of DnaA |
| MW, pI | 13 kDa, 6.065 |
| Gene length, protein length | 357 bp, 119 aa |
| Immediate neighbours | yaaT, yabB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU00330
Phenotypes of a mutant
strongly reduced growth rate in minimal medium PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: negative control of replication initiation PubMed
- Protein family: yabA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: leucine zipper
- Modification:
- Cofactor(s): Zn cluster
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P37542
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Philippe Noirot, Jouy-en-Josas, France Homepage
Alan Grossman, Cambridge, MA, USA Homepage
Your additional remarks
References
Reviews
Tsutomu Katayama, Shogo Ozaki, Kenji Keyamura, Kazuyuki Fujimitsu
Regulation of the replication cycle: conserved and diverse regulatory systems for DnaA and oriC.
Nat Rev Microbiol: 2010, 8(3);163-70
[PubMed:20157337]
[WorldCat.org]
[DOI]
(I p)
Original publications
