Difference between revisions of "RNA polymerase"

From SubtiWiki
Jump to: navigation, search
(Important original publications)
Line 25: Line 25:
 
<pubmed> 12732296 12581657 11297923 </pubmed>
 
<pubmed> 12732296 12581657 11297923 </pubmed>
 
===Important original publications===
 
===Important original publications===
<pubmed> 20724389 20817769 </pubmed>
+
<pubmed> 20817769 </pubmed>
 +
<pubmed> 20724389 </pubmed>

Revision as of 08:31, 27 October 2010

The enzyme responsible for transcription

Components of the RNA polymerase

Core subunits

Sigma factors

  • In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)

Small accessory subunits

  • RpoE: delta subunit
  • YloH: omega subunit

Other temporary components

  • NusA: essential elongation factor

References

Reviews

P J Lewis, G P Doherty, J Clarke
Transcription factor dynamics.
Microbiology (Reading): 2008, 154(Pt 7);1837-1844
[PubMed:18599813] [WorldCat.org] [DOI] (P p)

Kristina M Herbert, William J Greenleaf, Steven M Block
Single-molecule studies of RNA polymerase: motoring along.
Annu Rev Biochem: 2008, 77;149-76
[PubMed:18410247] [WorldCat.org] [DOI] (P p)

W G Haldenwang
The sigma factors of Bacillus subtilis.
Microbiol Rev: 1995, 59(1);1-30
[PubMed:7708009] [WorldCat.org] [DOI] (P p)

The structure of RNA polymerase

Important original publications