Difference between revisions of "RNA polymerase"

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(Created page with "=='''The enzyme responsible for transcription'''== ==Components of the RNA polymerase== ===Core subunits=== * RpoA: alpha subunit * RpoB: beta subunit * RpoC: beta' ...")
 
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===Small accessory subunits===
 
===Small accessory subunits===
* [[RpoD]]: delta subunit
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* [[RpoE]]: delta subunit
 
* [[YloH]]: omega subunit
 
* [[YloH]]: omega subunit
  

Revision as of 16:54, 21 August 2010

The enzyme responsible for transcription

Components of the RNA polymerase

Core subunits

Sigma factors

  • In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)

Small accessory subunits

  • RpoE: delta subunit
  • YloH: omega subunit

References

Reviews

P J Lewis, G P Doherty, J Clarke
Transcription factor dynamics.
Microbiology (Reading): 2008, 154(Pt 7);1837-1844
[PubMed:18599813] [WorldCat.org] [DOI] (P p)

Kristina M Herbert, William J Greenleaf, Steven M Block
Single-molecule studies of RNA polymerase: motoring along.
Annu Rev Biochem: 2008, 77;149-76
[PubMed:18410247] [WorldCat.org] [DOI] (P p)

W G Haldenwang
The sigma factors of Bacillus subtilis.
Microbiol Rev: 1995, 59(1);1-30
[PubMed:7708009] [WorldCat.org] [DOI] (P p)

The structure of RNA polymerase

Important original publications

Geoff P Doherty, Mark J Fogg, Anthony J Wilkinson, Peter J Lewis
Small subunits of RNA polymerase: localization, levels and implications for core enzyme composition.
Microbiology (Reading): 2010, 156(Pt 12);3532-3543
[PubMed:20724389] [WorldCat.org] [DOI] (I p)