DacC

• Description: penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
  
  

Gene name	dacC
Synonyms	pbp
Essential	no
Product	penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
Function	carboxypeptidase
MW, pI	52 kDa, 5.413
Gene length, protein length	1473 bp, 491 aa
Immediate neighbours	ppsA, galM
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU18350

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

cell wall synthesis

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: cleavage ofD-Ala-D-Ala interpeptide bridges in peptidoglycan PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1W5D, 2J9P (complex with a peptidoglycan mimetic peptide)

• UniProt: P39844

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: galM-dacC PubMed

• Sigma factor: SigH PubMed, SigB PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: