Difference between revisions of "PreQ1 riboswitch"

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(Structure of this riboswitch)
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==Structure of this riboswitch==
 
==Structure of this riboswitch==
  
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This [[riboswitch]] controls the expression of the ''[[queC]]-[[queD]]-[[queE]]-[[queF]]'' operon in response to the availability of queuosine. In the absence of queuosine, the [[riboswitch]] allows transcriptional antitermination.
 
<pubmed>19285444,17384645  19234468</pubmed>
 
<pubmed>19285444,17384645  19234468</pubmed>

Revision as of 20:48, 17 June 2010

Structure of this riboswitch

This riboswitch controls the expression of the queC-queD-queE-queF operon in response to the availability of queuosine. In the absence of queuosine, the riboswitch allows transcriptional antitermination.

Mijeong Kang, Robert Peterson, Juli Feigon
Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA.
Mol Cell: 2009, 33(6);784-90
[PubMed:19285444] [WorldCat.org] [DOI] (I p)

Daniel J Klein, Thomas E Edwards, Adrian R Ferré-D'Amaré
Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase.
Nat Struct Mol Biol: 2009, 16(3);343-4
[PubMed:19234468] [WorldCat.org] [DOI] (I p)

Adam Roth, Wade C Winkler, Elizabeth E Regulski, Bobby W K Lee, Jinsoo Lim, Inbal Jona, Jeffrey E Barrick, Ankita Ritwik, Jane N Kim, Rüdiger Welz, Dirk Iwata-Reuyl, Ronald R Breaker
A riboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain.
Nat Struct Mol Biol: 2007, 14(4);308-17
[PubMed:17384645] [WorldCat.org] [DOI] (P p)