YtxM

• Description: similar to prolyl aminopeptidase
  
  

Gene name	ytxM
Synonyms	ytfB
Essential	no
Product	unknown
Function	ubiquinone and menaquinone biosynthesis
Metabolic function and regulation of this protein in SubtiPathways: Menaquinone
MW, pI	30 kDa, 7.175
Gene length, protein length	822 bp, 274 aa
Immediate neighbours	menB, menD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU30810

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

biosynthesis of cofactors

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: lipase/esterase LIP3/bchO family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P23974

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: menF-menD-ytxM-menB-menE-menC PubMed

• Sigma factor: SigA: PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

M M Mehanni, A P Turnbull, S E Sedelnikova, P J Baker, S Foster, D W Rice
Crystallization and preliminary X-ray analysis of the ytxM gene product from Bacillus subtilis.
Acta Crystallogr D Biol Crystallogr: 2002, 58(Pt 12);2138-40
[PubMed:12454479] [WorldCat.org] [DOI] (P p)

H Antelmann, C Scharf, M Hecker
Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis.
J Bacteriol: 2000, 182(16);4478-90
[PubMed:10913081] [WorldCat.org] [DOI] (P p)

Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221] [WorldCat.org] [DOI] (P p)

X Qin, H W Taber
Transcriptional regulation of the Bacillus subtilis menp1 promoter.
J Bacteriol: 1996, 178(3);705-13
[PubMed:8550504] [WorldCat.org] [DOI] (P p)

J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163] [WorldCat.org] [DOI] (P p)