YrkQ

• Description: two-component sensor kinase
  
  

Gene name	yrkQ
Synonyms
Essential	no
Product	two-component sensor kinase
Function	unknown
MW, pI	49 kDa, 5.16
Gene length, protein length	1296 bp, 432 aa
Immediate neighbours	yrkR, yrkP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU26420

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

protein modification, transcription factors and their control, membrane proteins, phosphoproteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YrkP

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YrkQ-YrkP

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P54444

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yrkP-yrkQ-yrkR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • YrkP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Taku Ohsawa, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YrkP.
Biosci Biotechnol Biochem: 2008, 72(1);186-96
[PubMed:18175906] [WorldCat.org] [DOI] (I p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)