Kbl

• Description: 2-amino-3-ketobutyrate CoA ligase
  
  

Gene name	kbl
Synonyms
Essential	no
Product	2-amino-3-ketobutyrate CoA ligase
Function	threonine utilization
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr
MW, pI	43 kDa, 6.25
Gene length, protein length	1176 bp, 392 aa
Immediate neighbours	tdh, ymcB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU17000

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

utilization of amino acids

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate (according to Swiss-Prot)

• Protein family: class-II pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1FC4 (from Escherichia coli, 40% identity, 60% similarity) PubMed

• UniProt: O31777

• KEGG entry: [2]

• E.C. number: 2.3.1.29

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: