RibC

• Description: riboflavin kinase / FAD synthase
  
  

Gene name	ribC
Synonyms
Essential	no
Product	riboflavin kinase / FAD synthase
Function	FAD biosynthesis
Metabolic function and regulation of this protein in SubtiPathways: Riboflavin / FAD
MW, pI	35 kDa, 8.3
Gene length, protein length	948 bp, 316 aa
Immediate neighbours	truB, rpsO
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU16670

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

biosynthesis of cofactors

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + riboflavin = ADP + FMN (according to Swiss-Prot)

• Protein family: ribF family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1S4M (from Thermotoga maritima, 33% identity, 54% similarity) PubMed

• UniProt: P54575

• KEGG entry: [2]

• E.C. number: 2.7.1.26, 2.7.7.2

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Weiru Wang, Rosalind Kim, Hisao Yokota, Sung-Hou Kim
Crystal structure of flavin binding to FAD synthetase of Thermotoga maritima.
Proteins: 2005, 58(1);246-8
[PubMed:15468322] [WorldCat.org] [DOI] (I p)