Difference between revisions of "PurA"
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− | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KJX 1KJX] (from ''Escherichia coli k12'', 46% identity, 64% similarity) {{PubMed|11741996}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P29726 P29726] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P29726 P29726] |
Revision as of 13:53, 19 February 2010
- Description: adenylosuccinate synthetase
Gene name | purA |
Synonyms | |
Essential | no |
Product | adenylosuccinate synthetase |
Function | purine biosynthesis |
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Purine synthesis, Nucleotides (regulation) | |
MW, pI | 47 kDa, 5.459 |
Gene length, protein length | 1290 bp, 430 aa |
Immediate neighbours | trnY-Lys, yycE |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU40420
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP (according to Swiss-Prot)
- Protein family: adenylosuccinate synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P29726
- KEGG entry: [3]
- E.C. number: 6.3.4.4
Additional information
Expression and regulation
- Operon: purA PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References