Difference between revisions of "AcpA"
| Line 78: | Line 78: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1F80 1F80] (complex with [[AcpS]]) {{PubMed|10997907}}, [http://www.rcsb.org/pdb/explore.do?structureId=3EJE 3EJE] (complex with [[BioI]]), [http://www.rcsb.org/pdb/explore.do?structureId=1HY8 1HY8] | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1F80 1F80] (complex with [[AcpS]]) {{PubMed|10997907}}, [http://www.rcsb.org/pdb/explore.do?structureId=3EJE 3EJE] (complex with [[BioI]]) {{PubMed|18838690}}, [http://www.rcsb.org/pdb/explore.do?structureId=1HY8 1HY8] |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P80643 P80643] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P80643 P80643] | ||
| Line 128: | Line 128: | ||
<pubmed> 15952903 </pubmed> | <pubmed> 15952903 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>10997907,19850612, 12737802</pubmed> | + | <pubmed>10997907,19850612, 12737802 18838690 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:40, 6 January 2010
- Description: acyl carrier protein
| Gene name | acpA |
| Synonyms | acpP |
| Essential | yes PubMed |
| Product | acyl carrier protein |
| Function | fatty acid biosynthesis |
| MW, pI | 8 kDa, 3.594 |
| Gene length, protein length | 231 bp, 77 aa |
| Immediate neighbours | fabG, rnc |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU15920
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot), during sporulation in the mother cell PubMed
Database entries
- UniProt: P80643
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Diego de Mendoza, Universidad Nacional de Rosario, Argentine homepage
Your additional remarks
References
Reviews
Original Publications
Mariano A Martinez, Diego de Mendoza, Gustavo E Schujman
Transcriptional and functional characterization of the gene encoding acyl carrier protein in Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 2);484-495
[PubMed:19850612]
[WorldCat.org]
[DOI]
(I p)
Max J Cryle, Ilme Schlichting
Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc Natl Acad Sci U S A: 2008, 105(41);15696-701
[PubMed:18838690]
[WorldCat.org]
[DOI]
(I p)
Gustavo E Schujman, Luciana Paoletti, Alan D Grossman, Diego de Mendoza
FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis.
Dev Cell: 2003, 4(5);663-72
[PubMed:12737802]
[WorldCat.org]
[DOI]
(P p)
K D Parris, L Lin, A Tam, R Mathew, J Hixon, M Stahl, C C Fritz, J Seehra, W S Somers
Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites.
Structure: 2000, 8(8);883-95
[PubMed:10997907]
[WorldCat.org]
[DOI]
(P p)
