Difference between revisions of "Mta"

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(Labs working on this gene/protein)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''mta'' {{PubMed|9353933}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|10200972}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** positive autoregulation {{PubMed|10200972}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** Mta: transcription activation {{PubMed|10200972}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>18502870,14985361,11581256,11053850,10200972 </pubmed>
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<pubmed>18502870,14985361,11581256,11053850,10200972 9353933 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:11, 2 February 2010

  • Description: transcriptional activator of multidrug-efflux transporter genes, activates ymfD expression

Gene name mta
Synonyms ywnD
Essential no
Product transcriptional activator
Function regulation of multidrug-efflux transporter genes
MW, pI 29 kDa, 4.949
Gene length, protein length 771 bp, 257 aa
Immediate neighbours clsA, ywnC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Mta context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU36600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 1JBG (N-terminal domain), 1R8D (complex of N-terminal domain with DNA)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • positive autoregulation PubMed
  • Regulatory mechanism:
    • Mta: transcription activation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Mohamed Marahiel, Marburg University, Germany homepage

Richard Brennan, Houston, Texas, USA Homepage

Your additional remarks

References