Difference between revisions of "PhoR"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[phoP]]-[[phoR]]'' | + | * '''Operon:''' ''[[phoP]]-[[phoR]]'' {{PubMed|14762014}} |
| − | * '''[[Sigma factor]]:''' [[SigA]], [[SigE]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|16452408}}, [[SigB]] {{PubMed|15205429}}, [[SigE]] {{PubMed|15699190,15205429}} |
| − | * '''Regulation:''' | + | * '''Regulation:''' |
| + | ** carbon catabolite repression ([[CcpA]]) {{PubMed|16452408}} | ||
** expressed under conditions of phosphate limitation ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15205429,14762014 PubMed] | ** expressed under conditions of phosphate limitation ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15205429,14762014 PubMed] | ||
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' |
| + | ** [[CcpA]]: transcription repression {{PubMed|16452408}} | ||
** [[PhoP]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/15205429,14762014 PubMed] | ** [[PhoP]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/15205429,14762014 PubMed] | ||
| Line 121: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed>10433720,15205429,9084179,17085571,9987123,10913081,10094672,,15205429,14762014, 20008068 </pubmed> | + | <pubmed>10433720,15205429,9084179,17085571,9987123,10913081,10094672,16452408 ,15205429,14762014, 20008068 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:50, 17 December 2009
- Description: two-component sensor kinase, regulation of phosphate metabolism
| Gene name | phoR |
| Synonyms | |
| Essential | no |
| Product | two-component sensor kinase |
| Function | regulation of phosphate metabolism |
| MW, pI | 64 kDa, 5.957 |
| Gene length, protein length | 1737 bp, 579 aa |
| Immediate neighbours | polA, phoP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU29100
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of PhoP
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
- Modification: autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: P23545
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Marion Hulett, University of Illinois at Chicago, USA Homepage
Your additional remarks
References
