Difference between revisions of "PhrF"
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=Expression and regulation= | =Expression and regulation= | ||
− | |||
* '''Operon:''' | * '''Operon:''' | ||
+ | ** ''[[rapF]]-[[phrF]]'' {{PubMed|11466295}} | ||
+ | ** ''[[phrF]]'' {{PubMed|11466295}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
+ | ** ''[[phrF]]'': [[SigH]] {{PubMed|11466295}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[ComA]]: transcription activation {{PubMed|15968044} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
− | <pubmed>16816200,15968044, </pubmed> | + | <pubmed>16816200,15968044, 11466295</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 20:06, 3 February 2010
- Description: response regulator aspartate phosphatase (RapF) regulator
Gene name | phrF |
Synonyms | ywhI |
Essential | no |
Product | phosphatase (RapF) regulator |
Function | control of ComA activity |
MW, pI | 4 kDa, 10.237 |
Gene length, protein length | 117 bp, 39 aa |
Immediate neighbours | rapF, ywhH |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU37470
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to RapF, this results in the inability of RapF to interact with ComA PubMed
- Protein family: phr family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P71001
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- ComA: transcription activation {{PubMed|15968044}
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
Modulation of the ComA-dependent quorum response in Bacillus subtilis by multiple Rap proteins and Phr peptides.
J Bacteriol: 2006, 188(14);5273-85
[PubMed:16816200]
[WorldCat.org]
[DOI]
(P p)
Cristina Bongiorni, Shu Ishikawa, Sophie Stephenson, Naotake Ogasawara, Marta Perego
Synergistic regulation of competence development in Bacillus subtilis by two Rap-Phr systems.
J Bacteriol: 2005, 187(13);4353-61
[PubMed:15968044]
[WorldCat.org]
[DOI]
(P p)
R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295]
[WorldCat.org]
[DOI]
(P p)