Difference between revisions of "YxdK"
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− | * '''Description:''' [[two-component systems|two-component]] sensor kinase <br/><br/> | + | * '''Description:''' [[two-component systems|two-component]] sensor kinase, regulation of the [[ABC transporter]] [[YxdL]]-[[YxdM]] in response to the cationic antimicrobial peptide, LL-37 <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] sensor kinase | |style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] sensor kinase | ||
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− | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || resistance against toxic peptides |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 6.226 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 6.226 | ||
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=References= | =References= | ||
− | <pubmed>10094672,10746760,17600057,, </pubmed> | + | <pubmed>10094672,10746760,17600057, 21078927, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 17:54, 17 November 2010
- Description: two-component sensor kinase, regulation of the ABC transporter YxdL-YxdM in response to the cationic antimicrobial peptide, LL-37
Gene name | yxdK |
Synonyms | |
Essential | no |
Product | two-component sensor kinase |
Function | resistance against toxic peptides |
MW, pI | 37 kDa, 6.226 |
Gene length, protein length | 975 bp, 325 aa |
Immediate neighbours | yxdL, yxdJ |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU39650
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YxdJ
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
- Modification: autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P42422
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References