Difference between revisions of "ArsC"
| Line 70: | Line 70: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[ArsC]]-[[TrxA]] | + | * '''Interactions:''' [[ArsC]]-[[TrxA]] {{PubMed|17303556}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 76: | Line 76: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Z2D 1Z2D] (reduced form), [http://www.rcsb.org/pdb/explore.do?structureId=1Z2E 1Z2E] (oxidized form), [http://www.rcsb.org/pdb/explore.do?structureId=2IPA 2IPA] (TrxA- | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Z2D 1Z2D] (reduced form), [http://www.rcsb.org/pdb/explore.do?structureId=1Z2E 1Z2E] (oxidized form), [http://www.rcsb.org/pdb/explore.do?structureId=2IPA 2IPA] (TrxA-ArsC-complex) {{PubMed|17303556}}, [http://www.rcsb.org/pdb/explore.do?structureId=1JL3 1JL3] |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P45947 P45947] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P45947 P45947] | ||
| Line 120: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>9537360,16497325,11679756,,9537360, </pubmed> | + | <pubmed>9537360,16497325,11679756,,9537360, 17303556</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 06:39, 24 February 2010
- Description: arsenate reductase
| Gene name | arsC |
| Synonyms | yqcM |
| Essential | no |
| Product | arsenate reductase |
| Function | detoxification of arsenate |
| MW, pI | 15 kDa, 4.749 |
| Gene length, protein length | 417 bp, 139 aa |
| Immediate neighbours | spoIVCA, arsB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU25780
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
- Protein family: ArsC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: P45947
- KEGG entry: [3]
- E.C. number: 3.1.3.48
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
You Li, Yunfei Hu, Xinxin Zhang, Huimin Xu, Ewen Lescop, Bin Xia, Changwen Jin
Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
J Biol Chem: 2007, 282(15);11078-83
[PubMed:17303556]
[WorldCat.org]
[DOI]
(P p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Z Guan, L Hederstedt, J Li, X D Su
Preparation and crystallization of a Bacillus subtilis arsenate reductase.
Acta Crystallogr D Biol Crystallogr: 2001, 57(Pt 11);1718-21
[PubMed:11679756]
[WorldCat.org]
[DOI]
(P p)
T Sato, Y Kobayashi
The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite.
J Bacteriol: 1998, 180(7);1655-61
[PubMed:9537360]
[WorldCat.org]
[DOI]
(P p)
