YpwA

• Description: carboxypeptidase, metalloprotease
  
  

Gene name	ypwA
Synonyms
Essential	no
Product	M32 carboxypeptidase
Function	unknown
MW, pI	58 kDa, 4.77
Gene length, protein length	1503 bp, 501 aa
Immediate neighbours	xpt, kdgT
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU22080

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

proteolysis

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: M32 carboxypeptidase

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: dimer PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 3HQ2 PubMed

• UniProt: P50848

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ypwA (according to DBTBS)

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Marianne M Lee, Clara E Isaza, James D White, Rita P-Y Chen, George F-C Liang, Hannah T-F He, Sunney I Chan, Michael K Chan
Insight into the substrate length restriction of M32 carboxypeptidases: characterization of two distinct subfamilies.
Proteins: 2009, 77(3);647-57
[PubMed:19544567] [WorldCat.org] [DOI] (I p)