Difference between revisions of "SftA"
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|''sftA'' | |''sftA'' | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytpS '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytpS, cdtA '' |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity {{PubMed|19818024}} |
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' forms a hexamer {{PubMed|19818024}} |
* '''Localization:''' Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed], co-localizes with [[FtsZ]] at nascent division sites {{PubMed|19788545}} | * '''Localization:''' Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed], co-localizes with [[FtsZ]] at nascent division sites {{PubMed|19788545}} | ||
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=References= | =References= | ||
| − | <pubmed>16479537 19788545 </pubmed> | + | <pubmed>16479537 19788545 19818024 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:36, 13 October 2009
- Description: DNA translocase
| Gene name | sftA |
| Synonyms | ytpS, cdtA |
| Essential | no |
| Product | DNA translocase |
| Function | resolution of chromosome dimers |
| MW, pI | 30 kDa, 9.955 |
| Gene length, protein length | 792 bp, 264 aa |
| Immediate neighbours | murC, ytpR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29805
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity PubMed
- Protein family:
- Paralogous protein(s): SpoIIIE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: forms a hexamer PubMed
- Localization: Cytoplasm (Homogeneous) PubMed, co-localizes with FtsZ at nascent division sites PubMed
Database entries
- Structure:
- UniProt: C0SP86
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Christine Kaimer, José Eduardo González-Pastor, Peter L Graumann
SpoIIIE and a novel type of DNA translocase, SftA, couple chromosome segregation with cell division in Bacillus subtilis.
Mol Microbiol: 2009, 74(4);810-25
[PubMed:19818024]
[WorldCat.org]
[DOI]
(I p)
Steven J Biller, William F Burkholder
The Bacillus subtilis SftA (YtpS) and SpoIIIE DNA translocases play distinct roles in growing cells to ensure faithful chromosome partitioning.
Mol Microbiol: 2009, 74(4);790-809
[PubMed:19788545]
[WorldCat.org]
[DOI]
(I p)
Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537]
[WorldCat.org]
[DOI]
(P p)
