Difference between revisions of "PutC"
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=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' ''[[ycgM]]-[[ycgN]]'' (according to [http://dbtbs.hgc.jp/COG/prom/ycgMN.html DBTBS]) | |
| − | * '''Operon:''' ''[[ycgM]]-[[ycgN]] | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
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* '''Additional information:''' | * '''Additional information:''' | ||
| + | ** overexpressed in a ''[[pnpA]]'' mutant {{PubMed|14976255}} | ||
=Biological materials = | =Biological materials = | ||
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=References= | =References= | ||
| − | <pubmed>12618455,, </pubmed> | + | <pubmed>12618455,14976255, 14651647 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:39, 13 February 2010
- Description: 1-pyrroline-5-carboxylate dehydrogenase
| Gene name | ycgN |
| Synonyms | |
| Essential | no |
| Product | 1-pyrroline-5-carboxylate dehydrogenase |
| Function | proline utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate | |
| MW, pI | 56 kDa, 5.372 |
| Gene length, protein length | 1545 bp, 515 aa |
| Immediate neighbours | ycgM, ycgO |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03210
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-1-pyrroline-5-carboxylate + NAD(P)+ + 2 H2O = L-glutamate + NAD(P)H (according to Swiss-Prot)
- Protein family: RocA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P94391
- KEGG entry: [3]
- E.C. number: 1.5.1.12
Additional information
Expression and regulation
- Regulation:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Gintaras Deikus, Paul Babitzke, David H Bechhofer
Recycling of a regulatory protein by degradation of the RNA to which it binds.
Proc Natl Acad Sci U S A: 2004, 101(9);2747-51
[PubMed:14976255]
[WorldCat.org]
[DOI]
(P p)
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455]
[WorldCat.org]
[DOI]
(P p)
