YcbL

• Description: two-component response regulator
  
  

Gene name	ycbL
Synonyms
Essential	no
Product	two-component response regulator
Function	unknown
MW, pI	25 kDa, 4.917
Gene length, protein length	678 bp, 226 aa
Immediate neighbours	ycbK, ycbM
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU02550

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: OmpR family of two-component response regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation by YcbM ( on an aspartate residue, putative)

• Cofactor(s):

• Effectors of protein activity: activity is controlled by YcbM-dependent phosphorylation (putative)

• Interactions: YcbM-YcbL (putative)

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P42244

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ycbL-ycbM (according to DBTBS)

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)