BmrD

• Description: similar to ABC transporter (ATP-binding protein), also involved in the signalling pathway to activate KinA at the onset of sporulation
  
  

Gene name	yheH
Synonyms
Essential	no
Product	multidrug ABC transporter (ATP-binding protein)
Function	multiple antibiotic resistance
MW, pI	76 kDa, 7.082
Gene length, protein length	2019 bp, 673 aa
Immediate neighbours	yheI, yheG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU09720

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YheI-YheH PubMed

• Localization:

Database entries

• Structure:

• UniProt: O07549

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Cristina Torres, Carmen Galián, Christoph Freiberg, Jean-Raphaël Fantino, Jean-Michel Jault
The YheI/YheH heterodimer from Bacillus subtilis is a multidrug ABC transporter.
Biochim Biophys Acta: 2009, 1788(3);615-22
[PubMed:19167342] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)