Difference between revisions of "Ptb"
Line 91: | Line 91: | ||
=Expression and regulation= | =Expression and regulation= | ||
− | + | * '''Operon:''' ''[[ptb]]-[[bcd]]-[[buk]]-[[lpdV]]-[[bkdAA]]-[[bkdAB]]-[[bkdB]]'' {{PubMed|12823818}} | |
− | * '''Operon:''' ''[[ptb]]-[[bcd]]-[[buk]]-[[lpdV]]-[[bkdAA]]-[[bkdAB]]-[[bkdB]]'' | ||
* '''[[Sigma factor]]:''' [[SigL]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] | * '''[[Sigma factor]]:''' [[SigL]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
− | ** | + | ** induced in the presence of isoleucine or valine ([[BkdR]]) {{PubMed|10094682}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] | ** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] | ||
+ | ** [[BkdR]]: transcription activation {{PubMed|10094682}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Line 124: | Line 124: | ||
=References= | =References= | ||
− | <pubmed>12427936,15241682, | + | <pubmed>12427936,15241682,12823818,10094682, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 21:30, 19 November 2009
- Description: phosphate butyryltransferase
Gene name | ptb |
Synonyms | yqiS, bkd |
Essential | no |
Product | phosphate butyryltransferase |
Function | utilization of branched-chain keto acids |
Metabolic function and regulation of this protein in SubtiPathways: Ile, Leu, Val | |
MW, pI | 31 kDa, 7.936 |
Gene length, protein length | 897 bp, 299 aa |
Immediate neighbours | bcd, bkdR |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU24090
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Butanoyl-CoA + phosphate = CoA + butanoylphosphate (according to Swiss-Prot)
- Protein family: phosphate acetyltransferase and butyryltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P54530
- KEGG entry: [3]
- E.C. number: 2.3.1.19
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References