Difference between revisions of "RapF"

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* '''Description:''' response regulator aspartate phosphatase <br/><br/>
+
* '''Description:''' response regulator aspartate phosphatase, controls [[ComA]] activity <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.18   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.18   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' control of [[ComA]] activity {{PubMed|15968044}}
  
 
* '''Protein family:''' RAP family (according to Swiss-Prot)
 
* '''Protein family:''' RAP family (according to Swiss-Prot)
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* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:'''
+
* '''Effectors of protein activity:''' binding of [[PhrF]] to [[RapF]] prevents it from binding [[ComA]] {{PubMed|15968044}}
  
* '''Interactions:'''
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* '''Interactions:''' [[RapF]]-[[ComA]] {{PubMed|15968044}}, [[RapF]]-[[PhrF]] {{PubMed|15968044}}
  
* '''Localization:'''
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* '''Localization:'''  
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
  
<pubmed>12850135, </pubmed>
+
<pubmed>12850135, 15968044</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:15, 29 November 2009

  • Description: response regulator aspartate phosphatase, controls ComA activity

Gene name rapF
Synonyms ywhJ
Essential no
Product response regulator aspartate phosphatase
Function control of ComA activity
MW, pI 45 kDa, 5.18
Gene length, protein length 1143 bp, 381 aa
Immediate neighbours ywhK, phrF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapF context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU37460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: control of ComA activity PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: binding of PhrF to RapF prevents it from binding ComA PubMed
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (5-fold) (CcpA) PubMed
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References