Difference between revisions of "RapD"
| Line 1: | Line 1: | ||
| − | * '''Description:''' response regulator aspartate phosphatase <br/><br/> | + | * '''Description:''' response regulator aspartate phosphatase, controls [[ComA]] activity <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | |style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]]-dependent gene expression |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 7.691 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 7.691 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' control of [[ComA]]-dependent gene expression {{PubMed|17227471}} |
* '''Protein family:''' RAP family (according to Swiss-Prot) | * '''Protein family:''' RAP family (according to Swiss-Prot) | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[rapD]]'' {{PubMed|9636707}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9636707}}, [[SigX]] {{PubMed|9636707}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed by [[RghR]] | + | ** repressed by [[RghR]] {{PubMed|17227471}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[RghR]]: transcription repression | + | ** [[RghR]]: transcription repression {{PubMed|17227471}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>17227471,9636707 | + | <pubmed>17227471,9636707, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 07:54, 29 November 2009
- Description: response regulator aspartate phosphatase, controls ComA activity
| Gene name | rapD |
| Synonyms | ywpA |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of ComA-dependent gene expression |
| MW, pI | 41 kDa, 7.691 |
| Gene length, protein length | 1062 bp, 354 aa |
| Immediate neighbours | ywpB, flhP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU36380
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P94583
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mitsuo Ogura, Yasutaro Fujita
Bacillus subtilis rapD, a direct target of transcription repression by RghR, negatively regulates srfA expression.
FEMS Microbiol Lett: 2007, 268(1);73-80
[PubMed:17227471]
[WorldCat.org]
[DOI]
(P p)
X Huang, J D Helmann
Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search.
J Mol Biol: 1998, 279(1);165-73
[PubMed:9636707]
[WorldCat.org]
[DOI]
(P p)
