Difference between revisions of "EpsB"

From SubtiWiki
Jump to: navigation, search
(Expression and regulation)
Line 87: Line 87:
  
 
=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]'' {{PubMed|15661000}}
  
* '''Operon:''' ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/15661000 PubMed]
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15661000}}
 
 
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15661000 PubMed]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed by [[SinR]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15661000 PubMed]
+
** repressed by [[SinR]] {{PubMed|15661000}}
  
* '''Regulatory mechanism:''' [[SinR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/15661000 PubMed]
+
* '''Regulatory mechanism:'''  
** [[SinR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/15661000 PubMed]
+
** [[SinR]]: transcription repression {{PubMed|15661000}}
 +
** [[SlrR]]: transcription activation {{PubMed|18647168}}
  
* '''Additional information:''' induction by sequestration of [[SinR]] by [[SinI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15661000 PubMed]
+
* '''Additional information:'''  
 +
** induction by sequestration of [[SinR]] by [[SinI]] {{PubMed|15661000}}
 +
** activation by [[SlrR]] requires prior formation of the [[SlrR]]-[[SlrA]] complex {{PubMed|18647168}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 09:25, 30 December 2009

  • Description: extracellular polysaccharide synthesis, putative protein tyrosine kinase

Gene name epsB
Synonyms yveL
Essential no
Product unknown
Function extracellular polysaccharide synthesis
MW, pI 24 kDa, 9.918
Gene length, protein length 681 bp, 227 aa
Immediate neighbours epsC, epsA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YveL context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU34360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate (according to Swiss-Prot)
  • Protein family: cpsD/capB family (according to Swiss-Prot)
  • Paralogous protein(s): PtkA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References