Difference between revisions of "PhrE"
| Line 1: | Line 1: | ||
| − | * '''Description:''' phosphatase (RapE) regulator <br/><br/> | + | * '''Description:''' phosphatase ([[RapE]]) regulator <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase (RapE) regulator | + | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase ([[RapE]]) regulator |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation | |style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation | ||
| Line 89: | Line 89: | ||
* '''Operon:''' | * '''Operon:''' | ||
| + | ** ''[[rapE]]-[[phrE]]'' {{PubMed|11466295,10629174}} | ||
| + | ** ''[[phrE]]'' {{PubMed|11466295}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ''[[phrE]]'': [[SigA]] {{PubMed|11466295}}, [[SigH]] {{PubMed|11466295}} | ||
* '''Regulation:''' repressed by glucose (10-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | * '''Regulation:''' repressed by glucose (10-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
| Line 120: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed>12618455,12850135, </pubmed> | + | <pubmed>12618455,12850135,11466295,10629174 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:30, 25 November 2009
- Description: phosphatase (RapE) regulator
| Gene name | phrE |
| Synonyms | |
| Essential | no |
| Product | phosphatase (RapE) regulator |
| Function | control of sporulation initiation |
| MW, pI | 4 kDa, 8.863 |
| Gene length, protein length | 132 bp, 44 aa |
| Immediate neighbours | rapE, yqzI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU25840
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: phr family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O32025
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
phrE: SigA PubMed, SigH PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455]
[WorldCat.org]
[DOI]
(P p)
R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295]
[WorldCat.org]
[DOI]
(P p)
M Jiang, R Grau, M Perego
Differential processing of propeptide inhibitors of Rap phosphatases in Bacillus subtilis.
J Bacteriol: 2000, 182(2);303-10
[PubMed:10629174]
[WorldCat.org]
[DOI]
(P p)
