Difference between revisions of "DgkA"
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| − | * '''Description:''' | + | * '''Description:''' undecaprenol kinase <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || undecaprenol kinase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of peptidoglycan |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 7.128 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 7.128 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' |
* '''Protein family:''' bacterial diacylglycerol kinase family (according to Swiss-Prot) | * '''Protein family:''' bacterial diacylglycerol kinase family (according to Swiss-Prot) | ||
| Line 85: | Line 85: | ||
=== Additional information=== | === Additional information=== | ||
| + | The gene is annotated in KEGG/MetaCyc/Swiss-Prot as diacylglycerol kinase EC 2.7.1.107. However, in the recently published paper (July 2007) by Jerga et al {{PubMed|17535816}}, the authors confirmed that ''dgkA'' is not a diacylglycerol kinase (DagK) but rather an undecaprenol kinase. This annotation was removed from Swiss-Prot as of November 2009. {{PubMed|19935659}} | ||
=Expression and regulation= | =Expression and regulation= | ||
| Line 118: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed>12923107,, </pubmed> | + | <pubmed>12923107, 17535816, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:34, 26 November 2009
- Description: undecaprenol kinase
| Gene name | dgkA |
| Synonyms | yqxF |
| Essential | no |
| Product | undecaprenol kinase |
| Function | biosynthesis of peptidoglycan |
| MW, pI | 12 kDa, 7.128 |
| Gene length, protein length | 342 bp, 114 aa |
| Immediate neighbours | cdd, yqfG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU25310
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: bacterial diacylglycerol kinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P19638
- KEGG entry: [2]
- E.C. number: 2.7.1.107
Additional information
The gene is annotated in KEGG/MetaCyc/Swiss-Prot as diacylglycerol kinase EC 2.7.1.107. However, in the recently published paper (July 2007) by Jerga et al PubMed, the authors confirmed that dgkA is not a diacylglycerol kinase (DagK) but rather an undecaprenol kinase. This annotation was removed from Swiss-Prot as of November 2009. PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
