Difference between revisions of "PckA"
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+ | [[Stephane Aymerich |Stephane Aymerich]], Microbiology and Molecular Genetics, INRA Paris-Grignon, France | ||
=Your additional remarks= | =Your additional remarks= |
Revision as of 16:56, 9 January 2009
- Description: phosphoenolpyruvate carboxykinase synthesises phosphoenolpyrovat out of oxalacetate
Gene name | pckA |
Synonyms | ppc |
Essential | no |
Product | phosphoenolpyruvate carboxykinase |
Function | synthesis of phosphoenolpyrovat |
MW, pI | 58,1 kDa, 5.12 |
Gene length, protein length | 1581 bp, 527 amino acids |
Immediate neighbours | metK, ytmB |
Gene sequence (+200bp) | Protein sequence |
Genetic context File:GenE context.gif |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO(2)
- Protein family: phosphoenolpyruvate carboxykinase [ATP] family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Nucleotide binding Domain (233–240)
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: Cytoplasm
Database entries
- Structure:
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Operon:
- Sigma factor: SigA
- Regulation: neg. regulated by YqzB, repressed (35-times) Glc, repressor CcpN
- Regulatory mechanism:
- Additional information:
Biological materials
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France