Difference between revisions of "FabG"

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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[fapR]]-[[plsX]]-[[fabD]]-[[fabG]]'' {{PubMed|12737802}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|16932747}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed unless the cells experience a lack of malonyl-CoA ([[FapR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12737802 PubMed]
+
** repressed unless the cells experience an accumulation of malonyl-CoA ([[FapR]]) {{PubMed|12737802}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[FapR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12737802 PubMed]
+
** [[FapR]]: transcription repression {{PubMed|12737802}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>12737802, </pubmed>
+
<pubmed>12737802, 16932747</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:01, 11 October 2009

  • Description: beta-ketoacyl-acyl carrier protein reductase

Gene name fabG
Synonyms ylpF
Essential yes PubMed
Product beta-ketoacyl-acyl carrier protein reductase
Function fatty acid biosynthesis
MW, pI 26 kDa, 8.091
Gene length, protein length 738 bp, 246 aa
Immediate neighbours fabD, acpA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FabG context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU15910

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH (according to Swiss-Prot)
  • Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed unless the cells experience an accumulation of malonyl-CoA (FapR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References