HutG

• Description: formiminoglutamate hydrolase
  
  

Gene name	hutG
Synonyms
Essential	no
Product	formiminoglutamate hydrolase
Function	histidine utilization
Metabolic function and regulation of this protein in SubtiPathways: His
MW, pI	34 kDa, 5.439
Gene length, protein length	957 bp, 319 aa
Immediate neighbours	hutI, hutM
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU39380

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: N-formimidoyl-L-glutamate + H₂O = L-glutamate + formamide (according to Swiss-Prot)

• Protein family: arginase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P42068

• KEGG entry: [3]

• E.C. number: 3.5.3.8

Expression and regulation

• Operon: hutP-hutH-hutU-hutI-hutG-hutM PubMed

• Sigma factor: SigA

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Juliane Ollinger, Kyung-Bok Song, Haike Antelmann, Michael Hecker, John D Helmann
Role of the Fur regulon in iron transport in Bacillus subtilis.
J Bacteriol: 2006, 188(10);3664-73
[PubMed:16672620] [WorldCat.org] [DOI] (P p)