Difference between revisions of "RsmG"

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m (moved GidB to RsmG)
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* '''Description:''' glucose-inhibited division protein <br/><br/>
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* '''Description:''' 7-methylguanosine methyltransferase specific for the 16S rRNA, glucose-inhibited division protein <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || glucose-inhibited division protein
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|style="background:#ABCDEF;" align="center"| '''Product''' || 7-methylguanosine methyltransferase specific for the 16S rRNA
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|style="background:#ABCDEF;" align="center"|'''Function''' || rRNA modification
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 6.603   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 6.603   
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
 +
low-level resistance to streptomycin, increased level of streptomycin-resistant rpsL mutants (200 times higher than in the wild type) {{PubMed|17573471}}
  
 
=== Database entries ===
 
=== Database entries ===
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
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* '''Catalyzed reaction/ biological activity:''' methylates the N7 position of nucleotide G535 in 16S rRNA {{PubMed|17573471}}
  
 
* '''Protein family:''' RNA methyltransferase rsmG family (according to Swiss-Prot)
 
* '''Protein family:''' RNA methyltransferase rsmG family (according to Swiss-Prot)
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=References=
 
=References=
 +
<pubmed>17573471 </pubmed>

Revision as of 10:34, 13 July 2009

  • Description: 7-methylguanosine methyltransferase specific for the 16S rRNA, glucose-inhibited division protein

Gene name gidB
Synonyms
Essential no
Product 7-methylguanosine methyltransferase specific for the 16S rRNA
Function rRNA modification
MW, pI 26 kDa, 6.603
Gene length, protein length 717 bp, 239 aa
Immediate neighbours noc, gidA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GidB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU41000

Phenotypes of a mutant

low-level resistance to streptomycin, increased level of streptomycin-resistant rpsL mutants (200 times higher than in the wild type) PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: methylates the N7 position of nucleotide G535 in 16S rRNA PubMed
  • Protein family: RNA methyltransferase rsmG family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References