Difference between revisions of "BacD"

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|style="background:#ABCDEF;" align="center"| '''Product''' || alanine-anticapsin ligase  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || alanine-anticapsin ligase  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the antibiotic bacilysin
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 4.679   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 4.679   
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[bacA]]-[[bacB]]-[[bacC]]-[[bacD]]-[[bacE]]-[[bacF]]'' {{PubMed|12372825}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CodY]]: transcription repression {{PubMed|12372825}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>15609023,16030213,, 19352016 </pubmed>
+
<pubmed>15609023,16030213,12372825, 19352016 </pubmed>

Revision as of 21:31, 9 July 2009

  • Description: alanine-anticapsin ligase

Gene name bacD
Synonyms ywfE, ipa-83d
Essential no
Product alanine-anticapsin ligase
Function biosynthesis of the antibiotic bacilysin
MW, pI 52 kDa, 4.679
Gene length, protein length 1416 bp, 472 aa
Immediate neighbours bacE, bacC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwfE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU37710

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References