Difference between revisions of "MsrB"
| Line 78: | Line 78: | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1XM0 1XM0] | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1XM0 1XM0] | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P54155 P54155] |
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU21680] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU21680] | ||
Revision as of 13:13, 20 July 2009
- Description: peptide methionine sulfoxide reductase
| Gene name | msrB |
| Synonyms | yppQ |
| Essential | |
| Product | peptide methionine sulfoxide reductase |
| Function | regeneration of methionine and restoration of protein function after oxidative damage |
| MW, pI | 16 kDa, 5.842 |
| Gene length, protein length | 429 bp, 143 aa |
| Immediate neighbours | ypqP, msrA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU21680
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1XM0
- UniProt: P54155
- KEGG entry: [3]
- E.C. number: 1.8.4.12
Additional information
Expression and regulation
- Regulation: induced by oxidative stress (Spx)
- Regulatory mechanism: Spx: oxidized Spx binds RpoA and enhances msrA-msrB operon transcription PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
